Jagged 1產(chǎn)品信息
英文名稱:Protein jagged-1
中文名稱:Jagged-1蛋白
靶點別稱:CD339,JAG1,Jagged1,hJ1,JAGL1
物種:Human
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
無菌(Sterility)
The sterility testing was performed by membrane filtration method.
支原體(Mycoplasma)
Negative.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Jagged 1分子背景
蛋白jagged-1(JAG1)也稱為Jagged1、hJ1、JAGL1和CD339,它是一種單程I型膜蛋白,含有一個DSL結(jié)構(gòu)域和15個EGF樣結(jié)構(gòu)域。JAG1在成人和胎兒組織中廣泛表達,JAG1在宮頸鱗狀細(xì)胞癌中的表達上調(diào),在骨髓細(xì)胞系HS-27a中也有表達。JAG1是多種Notch受體的配體,參與Notch信號傳導(dǎo)的介導(dǎo)。JAG1參與哺乳動物心血管發(fā)育的早期和晚期。JAG1通過相似性抑制成肌細(xì)胞分化,并增強成纖維細(xì)胞生長因子誘導(dǎo)的血管生成(體外)。
關(guān)鍵字: Jagged 1;Jagged 1蛋白;CD339蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。