Netrin-1產(chǎn)品信息
英文名稱:Netrin 1
中文名稱:神經(jīng)軸突導(dǎo)向因子1
靶點(diǎn)別稱:Netrin-1,NTN1
物種:Human
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with NaCl with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Netrin-1分子背景
Netrin控制中樞神經(jīng)系統(tǒng)連合軸突和外周運(yùn)動軸突的引導(dǎo)。它與DCC或一些UNC5受體的結(jié)合將分別導(dǎo)致軸突吸引或排斥。與UNC5C結(jié)合可能會導(dǎo)致UNC5C與微管中聚合的TUBB3解離,從而導(dǎo)致微管動力學(xué)和軸突排斥增加。涉及背根神經(jīng)節(jié)軸突向脊髓的投射。它還通過與受體的結(jié)合作為一種存活因子,防止細(xì)胞凋亡的發(fā)生。通過調(diào)節(jié)細(xì)胞凋亡參與腫瘤發(fā)生。
關(guān)鍵字: Netrin-1;Netrin-1蛋白;Netrin-1重組蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。