中文名：依澤替米貝

英文名：Ezetimibe

中文別名：Zetia|Ezetrol|依澤替米貝|(3R,4S)-1-(4-氟苯基)-3-[(S)-3-(4-氟苯基)-3-羥基丙基]-4-(4-羥基苯基)-2-氮雜環(huán)丁酮|依折麥布

英文別名：Ezetimibe|163222-33-1|Zetia|Ezetrol|Ezedoc|Sch 58235|SCH58235|(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one|SCH-58235|(-)-Sch 58235|ezetimiba|ezetimibum|UNII-EOR26LQQ24|(3R,4S)-1-(4-fluorophenyl)-

純度：≥99%

貨號(hào)：E126609

包裝：5g、1g、25g

Cas號(hào)：163222-33-1

存儲(chǔ)溫度：-20°C儲(chǔ)存

產(chǎn)品介紹：

Ezetimibe has been reported to be a cholesterol transport inhibitor. Mechanistic studies show that this compound directly affects Niemann-Pick C1-like 1 (NPC1L1) and prevents it from incorporating into clathrin-coated vesicles. NPC1L1 is a polytopic transmembrane protein that facilitates absorption of cholesterol via clathrin/AP2-mediated endocytosis. By binding to NPC1L1, ezetimibe prevents endocytosis of this protein therefore blocking cholesterol transfer across membranes. Ezetimibe is used clinically to lower plasma cholesterol levels.A cholesterol transport inhibitor that binds to NPC1L1

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