Product Name：Klotho-derived peptide 6
CAS No.：2102414-23-1
Synonyms：Klotho衍生肽6
Catalog No.：218P730
Brand：HongTide（上海鴻肽生物）
Description：Klotho-derived peptide 6是一種β-連環(huán)蛋白信號抑制劑多肽，是由30個氨基酸組成的直鏈多肽。在體外結合和螯合Wnt配體，阻止Wnt1誘導的纖連蛋白和α-平滑肌作用的表達。在糖尿病腎病的體內小鼠模型中，Klotho-derived peptide 6減少腎損傷，提高存活率，并防止腎小球中纖連蛋白和IV型膠原的積聚。
Klotho driven peptide 6 is a type of β- Chain protein signaling inhibitor peptide is a straight chain peptide composed of 30 amino acids. Binding and chelating Wnt ligands in vitro to prevent Wnt1 induced fibronectin and α- The expression of smooth muscle action. In the in vivo mouse model of diabetes nephropathy, Klotho derived peptide 6 reduces renal injury, improves survival rate, and prevents accumulation of fibronectin and type IV collagen in glomeruli.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | QPVVTLYHWDLPQRLQDAYGGWANRALADH |
Sequence(3-letter code) | H-Gln-Pro-Val-Val-Thr-Leu-Tyr-His-Trp-Asp-Leu-Pro-Gln-Arg-Leu-Gln-Asp-Ala-Tyr-Gly-Gly-Trp-Ala-Asn-Arg-Ala-Leu-Ala-Asp-His-OH |
Peptide Structure | 
|
Molecular Formula | C159H232N46O44 |
Molecular Weight | 3491.87 |
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關鍵字： 2102414-23-1;Klotho-derived pepti;2102414-23-1;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現有產品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內外眾多科研工作者提供了優(yōu)質的服務及產品。