Product Uses Include
Analysis of in vivo RhoA activation levels
Detection of compounds and proteins that enhance RhoA activity
Detection of compounds and proteins that inhibit RhoA activity
The activity of RhoA in cells (tissues) was studied qualitatively
Product Description
Background:
Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases.
Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell
motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts
and Ca 2+ sensitivity of smooth muscle contraction.
Tested Applications: IP/WB
Tested Applications: IF
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