Host:Rabbit
Target Protein:RhoA
IR:Immunogen Range:101-193/193
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:387
Swiss Prot:P61586
Source:KLH conjugated synthetic peptide derived from human RhoA:101-193/193
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:200-800)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Rabbit
Zebrafish
.
本品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： RhoA;RHOA_HUMAN;ARH12;ARH 12;ARHA;RHO12;RHOH12;Rho A;
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