TGFBR2產(chǎn)品信息
英文名稱:Transforming growth factor beta receptor 2
中文名稱:轉化生長因子β受體2
靶點別稱:TGFBR2,TGFR2,TGF-beta RII,TGFβR2
物種:Human / Mouse
屬性:Protein
標記:Biotin-labeled / Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
TGFBR2分子背景
TGF-β受體2型(TGFBR2或TGFR-2)也稱為TGF-βII型受體,轉化生長因子β受體II型,TbetaR II,TGFβR2是一種同二聚體或異六聚體,屬于蛋白激酶超家族、TKL-Ser/Thr蛋白激酶家族和TGFB受體亞家族。TGFR2/TGFBR2與TGF-β1/TGFB1和TGF-β3/TGFB3的親和力很高,與TGF-β2/TGFB2的親和力要低得多。這種II型受體與I型受體形成異二聚體復合物,對信號轉導至關重要。配體結合后,TGFR2自磷酸化其細胞質(zhì)結構域,隨后磷酸化下游分子,這些分子隨后進入細胞核并調(diào)節(jié)與細胞增殖相關的基因亞群的轉錄。
TGFBR2用戶評價
關鍵字: TGFBR2;TGFBR2蛋白;TGFR2;TGF-beta RII;TGFβR2;
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