LIGHT產(chǎn)品信息
英文名稱:Tumor necrosis factor superfamily member 14
中文名稱:腫瘤壞死因子超家族成員14
靶點別稱:CD258 antigen,CD258,HVEM-L,LIGHT,LTg,TNFSF14,TR2,HVEML
物種:Human / Mouse / Cynomolgus
屬性:Protein / Kits / Cell
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
LIGHT分子背景
腫瘤壞死因子配體超家族成員14(LIGHT)是一種腫瘤壞死因子(TNF)超家族配體,通過皰疹病毒進入介體(HVEM)和淋巴毒素β受體(LTbetaR)發(fā)出信號來調(diào)節(jié)T細胞免疫反應(yīng)。LIGHT已成為影響CTL介導(dǎo)的腫瘤排斥、同種異體排斥和移植物抗宿主病的T細胞共刺激信號的有力發(fā)起者。LIGHT的組成性表達導(dǎo)致組織破壞和自身免疫樣疾病綜合征。
LIGHT用戶評價
關(guān)鍵字: LIGHT;LIGHT蛋白;CD258;CD258蛋白;LIGHT抗原;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。