中文名:鵝去氧膽酸
英文名:Chenodeoxycholic acid
中文別名:鵝脫氧膽酸
英文別名:chenodeoxycholic acid|Chenodiol|474-25-9|Chenix|Chenic acid|Cdca|Chenodesoxycholic acid|Chenodeoxycholate|Gallodesoxycholic acid|Chendol|Anthropodeoxycholic acid|Anthropodesoxycholic acid|Anthropododesoxycholic acid|Chenofalk|Chenodesoxycholsaeure|Chenoco
純度:98%
貨號:C104902
包裝:100g、25g、5g
Cas號:474-25-9
存儲溫度:2-8°C儲存,避光
產(chǎn)品介紹:
Chenodeoxycholic Acid, Free Acid and its 7β-isomer ursodeoxycholic acid are potent (nanomolar affinity) selective inhibitors of DD2 (AKR1C2). These compounds were non-competitive inhibitors of AKR1D1 yielding Ki values of 3.2 μM for chenodeoxycholic acid. This chemical is a hydrophobic primary bile acid, which increases intracellular Ca2+ in rat hepatocyte couplets. Studies indicate that Chenodeoxycholic Acid induces apoptosis throμgh a PKC dependent pathway. It is known that Chenodeoxycholic Acid is essential in the metabolism of cholesterol via activation of nuclear receptors. This bile acid can also bind to BABP with a stoichiometery of 1:2. Alternate studies indicate that chenodeoxycholic acid can inhibit the expression of IL-6 and cell viability in QBC939 cells.An apoptosis inducer via PKC-dependent signalling pathway.
查看阿拉丁官網(wǎng)此產(chǎn)品相關(guān)對應(yīng)頁面:https://www.aladdin-e.com/zh_cn/C104902.html
上海阿拉丁生化科技股份有限公司
聯(lián)系商家時請?zhí)峒癱hemicalbook,有助于交易順利完成!
阿拉丁客服