中文名稱

鹽酸洛貝林中文同義詞Α-洛貝林鹽酸鹽;2-[6-(2-羥基-2-苯乙基)-1-甲基-2-呱啶基]-1-苯乙酮鹽酸鹽;(-)-洛貝林鹽酸鹽;鹽酸-L-山梗堿;鹽酸洛貝林/鹽酸山梗堿;洛貝林鹽酸鹽;山梗菜堿鹽酸鹽;山梗烷醇酮鹽酸鹽英文名稱alpha-Lobelinehydrochloride英文同義詞(-)-id;2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor;2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone;Lobelinhydrochloride;2-((2R,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone;LobelinHydrochlorde;2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONEHCL;2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONEHYDROCHLORIDECAS號134-63-4分子式C22H28ClNO2分子量373.92EINECS號205-150-2

鹽酸洛貝林性質(zhì)

熔點183-185°C(dec.)(lit.)比旋光度D20-43°(c=2)折射率-57.5°(C=1,H2O)儲存條件Inertatmosphere,RoomTemperature溶解度H2O:25Chemicalbookmg/mL形態(tài)powder顏色whitetooff-white旋光性(opticalactivity)[α]20/D56.8°,c=2inH2OMerck14,5551BRN3920196LogP3.610(est)

用途鹽酸洛貝林為反射性呼吸中樞興奮藥。由于刺激頸動脈體及主動脈弓化學(xué)感受器，反射性地興奮延髓呼吸中樞，對迷走神經(jīng)中樞和血管運動Chemicalbook中樞也同時有反射性的興奮作用；對植物神經(jīng)節(jié)先興奮而后阻斷。用于各種原因引起的呼吸抑制。常用于新生兒窒息，一氧化碳、阿片中毒等。