Rabbit Anti-CCL2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CCL2
IR:Immunogen Range:25-99/99
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6347
Swiss Prot:P13500
Source:KLH conjugated synthetic peptide derived from human CCL2:25-99/99
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: CCL2;C-C motif chemokine ;Monocyte chemoattrac;HC11;MCAF;Monocyte chemotactic;MCP-1;CCL2_HUMAN;
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