Rabbit Anti-Phospho-Cofilin (Ser3) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-Cofilin (Ser3)
IR:Immunogen Range:A(p-S)GV
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1072
Swiss Prot:P23528
Source:KLH conjugated Synthesised phosphopeptide derived from human Cofilin around the phosphorylation site of Ser3:A(p-S)GV
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Sheep
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-Cofilin (Ser;Cofilin (Phospho-Ser;Cofilin (Phospho S3);CFL 1;CFL;Cofilin 1;p18;COF1_HUMAN;
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