Product Name：Humanin (human)
CAS No.：330936-69-1
Synonyms：Humanin (human) trifluoroacetate；抗凋亡肽；Humanin
Catalog No.：163P02
Brand：HongTide（上海鴻肽生物）
Description：Humanin 是一種24個氨基酸組成的抗凋亡肽，是Bax抑制劑。Humanin可以阻止Bax從細胞質向線粒體的轉運，阻斷Bax由活性構象向活性構象的轉變。Humanin是一種線粒體相關肽，具有對抗 AD 相關神經(jīng)毒性的神經(jīng)保護作用，能夠抑制由家族性阿爾茨海默病基因和淀粉樣β蛋白（人）誘導的神經(jīng)元細胞死亡。Humanin 還可以改善動物的整體胰島素敏感性。Humanin還與衰老有關。
Humanin is an anti-apoptotic peptide composed of 24 amino acids and is a Bax inhibitor. Humanin can prevent the transport of Bax from cytoplasm to mitochondria, and block the transition of Bax from active conformation to active conformation. Humanin is a mitochondrial related peptide that has neuroprotective effects against AD related neurotoxicity and can inhibit amyloidosis caused by familial Alzheimer's disease genes β Protein (human) induced neuronal cell death. Humanin can also improve the overall insulin sensitivity of animals. Humanin is also related to aging.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | MAPRGFSCLLLLTSEIDLPVKRRA |
Sequence(3-letter code) | H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH |
Peptide Structure | 
|
Molecular Formula | C119H204N34O32S2 |
Molecular Weight | 2687.27 |
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上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內外眾多科研工作者提供了優(yōu)質的服務及產(chǎn)品。