Product Name：Dulaglutide
CAS No.：923950-08-7
Synonyms：Dulaglutide - solution in PBS；杜拉魯肽
Catalog No.：218P075
Brand：HongTide（上海鴻肽生物）
Description：杜拉魯肽是新型長(zhǎng)效GLP-1R激動(dòng)劑多肽，序列中包含31個(gè)氨基酸，由兩個(gè)具有DPP-4 抑制作用的GLP-1類(lèi)似物和人免疫球蛋白重鏈IgG4-Fc 片段融合得到，在臨床表現(xiàn)中其活性與內(nèi)源性GLP-1相似，半衰期為5天，能有效延緩腎臟的清除作用。FDA于2014 年9 月批準(zhǔn)杜拉魯肽皮下注射液上市。歐盟委員會(huì)于2014年12月批準(zhǔn)杜拉魯肽皮下注射液在歐洲上市。
Dulaglutide is a novel long-acting GLP-1R agonist peptide with a sequence containing 31 amino acids. It is obtained by fusion of two GLP-1 analogues with DPP-4 inhibition and human immunoglobulin heavy chain IgG4-Fc fragments. In clinical manifestations, its activity is similar to endogenous GLP-1, with a half-life of 5 days, and can effectively delay renal clearance. The FDA approved the marketing of Dulaglutide subcutaneous injection in September 2014. The European Commission approved the marketing of Dulaglutide subcutaneous injection in Europe in December 2014.
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGEGTFTSDVSSYLEEQAAKEFIAWLVKGGG |
Sequence(3-letter code) | H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gly-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C149H221N37O49 |
Molecular Weight | 3314.62 |
訂購(gòu)聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
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上海鴻肽生物科技有限公司（簡(jiǎn)稱(chēng)：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷(xiāo)售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來(lái)，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。