產(chǎn)品屬性:
產(chǎn)品名稱(chēng)
規(guī)格
CAS號(hào)
型號(hào)
Furazolidone
10mM*1mLinDMSO 1g
67-45-8
EY-Y0165709
Cas No.67-45-8
別名 N/A
化學(xué)名 N/A
分子式 C8H7N3O5
分子量 225.16
溶解度 DMSO : 10 mg/mL (44.41 mM);H2O : < 0.1 mg/mL (insoluble)
儲(chǔ)存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.Target: Antibacterial Furazolidone is a novel therapeutic strategy in AML patients. Furazolidone can Inhibit the bone-marrow transformation mediated by a series of leukemia fusion proteins. Furazolidone significantly inhibits proliferation of AML cell lines. Furazolidone induces apoptosis of the AML leukemic cells treatment with Furazolidone induces differentiation of AML cell lines.
[1]. Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8(8):e72335.
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