醋酸可的松
CAS No.: 50-04-4
分子量:402.5
分子式:C23H30O6
英文名:Cortisone Acetaate
本品為17α,21-二羥基孕甾-4- 烯-3,11,20- 三酮21- 醋酸酯。
【性狀】 本品為白色或幾乎白色的結(jié)晶性粉末;無臭,初無味,隨后有持久的苦 味。 本品在氯仿中易溶,在丙酮或二氧六環(huán)中略溶,在乙醇或乙醚中微溶,在水中不溶。 比旋度 取本品,精密稱定,加二氧六環(huán)溶解并定量稀釋制成每 1ml中含10mg的溶 液,依法測定(附錄Ⅵ E),比旋度為+210°至+217°。 吸收系數(shù) 取本品,精密稱定,加無水乙醇溶解并定量稀釋制成每1ml 中約含10μ g的溶液,照分光光度法(附錄Ⅳ A),在238nm 的波長處測定吸收度,吸收系數(shù)(E 1% 1cm)為375 ~405 。
Cortisone acetate
CAS No.: 50-04-4
Molecular Weight: 402.5
Molecular Formula: C23H30O6
English Name: Cortisone Acetaate
This product is 17α, 21 - dihydroxy pregnane -4-- ene -3,11,20 - trione 21 - acetate.
[Character] is white or almost white crystalline powder; odorless, tasteless early, followed by a lasting bitterness. This product is soluble in chloroform, acetone or dioxane, slightly soluble in ethanol or ether, slightly soluble in water insoluble. Than the rotation of this product, accurately weighed, dissolved in dioxane and added quantitatively diluted per 1ml contains 10mg of the solution, according to the determination (Appendix Ⅵ E), optical rotation of +210 ° to +217 °. Absorption coefficient of the product, accurately weighed, dissolved in ethanol and added quantitatively diluted per 1ml of solution containing about 10μ g, according to spectrophotometry (Appendix Ⅳ A), was measured at 238nm wavelength absorption, absorption coefficient (E 1% 1cm) 375 - 405.
關(guān)鍵字: 醋酸可的松 ;可的松 ;50-04-4
武漢大華偉業(yè)醫(yī)藥化工集團(tuán)有限公司以中國為基地,以先進(jìn)的化學(xué)技術(shù)、醫(yī)學(xué)技術(shù)為專業(yè)主體,是集科研、開發(fā)、生產(chǎn)經(jīng)營為一體高科技企業(yè)、公司座落在武漢市江岸經(jīng)濟(jì)開發(fā)區(qū)岱家山045號,占地面積200多畝,有1個(gè)中試車間,3個(gè)多用生產(chǎn)車間(2個(gè)化學(xué)合成車間,2個(gè)生物合成車間,公司職工160名,其中以知名專家為首,與優(yōu)秀技工緊密結(jié)合的40名專業(yè)技術(shù)人員,包括10名 高級工程師和15名工程師,是一支具有專業(yè)背景、朝氣蓬勃、有高度創(chuàng)造天賦的團(tuán)隊(duì)。
公司主要從事原料藥(API)及其中間體的研發(fā)和生產(chǎn)。根據(jù)國內(nèi)外市場需求,以研發(fā)為先導(dǎo),著重于新產(chǎn)品和創(chuàng)新工藝的工業(yè)化,現(xiàn)已開發(fā)投產(chǎn)20多種產(chǎn)品,已發(fā)展成為一個(gè)具備一定規(guī)模和實(shí)力的科研生