地塞米松

產(chǎn)品類別: 醫(yī)藥原料和中間體
產(chǎn)品含量: 99%
化學(xué)式: C22H29FO5
CAS編號: 1950-2-2
質(zhì)量標(biāo)準(zhǔn): usp26  
CA登記號：50-02-2
含量：99%
質(zhì)量標(biāo)準(zhǔn)：BP93 BP2000 USP26 EPIV
產(chǎn)品性狀：白色結(jié)晶粉末
用途：主要用于抗炎和抗過敏，適用于類風(fēng)濕性關(guān)節(jié)炎和其他膠原性疾病等。
地塞米松是人工合成的糖皮質(zhì)激素中生物作用最強的激素之一，僅需要很小的量即能達(dá)到與天然皮質(zhì)醇相似的作用，因其量小，分布在血中濃度很低，難以用常規(guī)放射免疫定量測定法測出，故對測定自身皮質(zhì)醇分泌量無影響。本試驗利用地塞米松這一特性，通過其對垂體、下丘腦分泌的促腎上腺皮質(zhì)激素和促腎上腺皮質(zhì)激素釋放激素的抑制作用，及由此引起腎上腺皮質(zhì)激素分泌減少的程度，來了解下丘腦-垂體-腎上腺軸功能是否高于正常，其可能的病變在那個器官。

Dexamethasone

Product Category: Pharmaceutical raw materials and intermediates
Product content: 99%
Chemical formula: C22H29FO5
CAS Number: 1950-2-2
Quality Standards: usp26
CA Registration No. :50-02-2
Content: 99%
Quality Standard: BP93 BP2000 USP26 EPIV
Properties: white crystalline powder
Uses: mainly used for anti-inflammatory and anti-allergic, for rheumatoid arthritis and other collagen diseases.
Dexamethasone is a synthetic glucocorticoid hormones in one of the strongest biological role, requires only a small amount of natural cortisol that can achieve a similar effect, because a small amount of the distribution in the blood concentration is very low, difficult with conventional radioimmunoassay method to measure the quantitative determination, it is on the determination of their own had no effect on cortisol secretion. The use of dexamethasone test this feature, through its pituitary, hypothalamus secretion of ACTH and corticotropin-releasing hormone inhibition, and thus reduce the secretion of adrenal hormones caused by the degree to understand the hypothalamus - pituitary - adrenal axis is higher than normal, which may be the disease in that organ