中文名稱

9，10-secocholesta-5Z，7E，10（19）-三烯-1α，3β，25-三醇；1.α，25-二羥基維生素D3；骨化三醇

英文名字

9，10-secocholesta-5Z，7E，10（19）-triene-1α，3β，25-triol； 1.alpha.，25-dihydroxy Vitamin D3； Calcitriol

供應商

開曼生物

產(chǎn)品貨號

71820-1

背景資料

Calcitriol （1.alpha.，25-dihydroxy Vitamin D3） is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3， the principal circulating form of Vitamin D. A second， tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium， and to increase the mineralization of bone via the direct stimulation of osteoblasts.

產(chǎn)品描述

Calcitriol is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin.{10412} Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3， the principal circulating form of Vitamin D. A second， tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors.{10312} The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium， and to increase the mineralization of bone via the direct stimulation of osteoblasts.{10411}

保存建議

建議您在收到開曼生物品牌的Calcitriol （1 mg）產(chǎn)品后置于-20度保存，產(chǎn)品有效期為365天.

其他

開曼生物向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應用于腫瘤、氧化氮、神經(jīng)學、凋亡、氧化性損傷、內(nèi)分泌學等不同研究領域.開曼生物可提供用于檢測的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關脂質(zhì)、脂肪酸、酶和抗體.