中文名稱

1，2，3-丙三羧酸，1，-1'-[1-（12-氨基-4，9，11-三羥基-2-甲基十三烷基）-2-（1-甲基戊基）-1，2-乙二基]酯；伏馬菌素B1

英文名字

1，2，3-propanetricarboxylic acid， 1，-1’-[1-（12-amino-4，9，11-trihydroxy-2-methyltridecyl）-2-（1-methylpentyl）-1，2-ethanediyl] ester； Fumonisin B1

供應(yīng)商

開曼生物

產(chǎn)品貨號(hào)

62580-10

背景資料

Fumonisin B1 is a mycotoxin produced from F. moniliforme， a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase （sphingosine N-acyltransferase）. Fumonisin B1 attenuates the response of P388D1 cells to PAF and LPS by inhibiting ceramide formation. It also blocks the apoptotic response of HaCaT cells to the antiproliferative drug hexadecylphosphocholine， again through inhibition of ceramide production. Incubation of Swiss 3T3 cells with fumonisin B1 results in both an altered cell morphology due to disruption of axonal growth and a decrease in cell proliferation.

產(chǎn)品描述

A mycotoxin produced from F. moniliforme that functions as an inhibitor of ceramide synthase （sphingosine N-acyltransferase）

保存建議

建議您在收到開曼生物品牌的Fumonisin B1 （10 mg）產(chǎn)品后置于-20度保存，產(chǎn)品有效期為365天.

其他

開曼生物向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.開曼生物可提供用于檢測(cè)的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體