D25 -46° (c = 2 in methanol)
沸點(diǎn)
796.05°C (rough estimate)
密度
1.1424 (rough estimate)
折射率
1.5280 (estimate)
儲(chǔ)存條件
Sealed in dry,2-8°C
酸度系數(shù)(pKa)
pKa 7.73(H2O t = 25 I = 0.167) (Uncertain)
水溶解性
H2O: soluble 50 mg/mL
穩(wěn)定性
Solutions are stable at pH 4-9 (most stable at pH 7);Below pH 4 tylosin B (desmycosin) is formed as a result of acid hydrolysis;In neutral and alkaline pH – tylosin aldol (TAD) is formed together with polar degradation products of unknown identity;When tylosin solution is exposed to daylight, a photodegradation product - isotylosin A (isoTA) is formed.
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