Asciminib (ABL001)是一種有效的、選擇性的ABL1變構(gòu)抑制劑,Kd值為0.5-0.8?nM,與ABL1的十四??诖Y(jié)合。
ABL001;ABL-001;ABL-001;AB-001;ABL001;ASCIMINIB;ASCIMINIBFREEBASE;;asciminibfreebase;(R)-N-(4-(CHLORODIFLUOROMETHOXY)PHENYL)-6-(3-HYDROXYPYRROLIDIN-1-YL)-5-(1H-PYRAZOL-5-YL)NICOTI;(R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide;ABL-001;Asciminib;EOS-61420
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