中文名稱
Thalidomide-O-amido-PEG3-C2-NH2 TFA
英文名稱
Thalidomide-O-amido-PEG3-C2-NH2 TFA
英文別名
Thalidomide-O-amido-PEG3-C2-NH2 TFA;Thalidomide-O-amido-PEG3-C2-NH2 (TFA);N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid;Conjugates 14;TQP0425;BCP30509;Cereblon Ligand-Linker Conjugates 3 (TFA);N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ac;E3 Ligase Ligand-Linker Conjugates 14
Cas No.
1957236-21-3
分子式
C25H31F3N4O11
分子量
620.53
包裝儲(chǔ)存
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
| 產(chǎn)品詳情 |
Thalidomide-O-amido-PEG3-C2-NH2 TFA 是一種合成的 E3 連接酶配體-linker 偶聯(lián)物，包含基于 Thalidomide 的 cereblon 配體和 3 個(gè)單元的 PEG linker。
| 生物活性 |
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
| 運(yùn)輸條件 |
Room temperature in continental US; may vary elsewhere.
| 儲(chǔ)存方式 |
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
| 參考文獻(xiàn) |
[1]. BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.