ZLN005 NEW
Price | $31 | $51 | $92 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: ZLN005 | CAS No.: 49671-76-3 |
Purity: 99.8% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | ZLN005 |
Description | ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α. |
In vitro | ZLN005 (15 mg/kg, p.o.) exhibits anti-hyperglycemic and anti-hyperlipidemic effects, and enhances insulin sensitivity in db/db mice without effecting lean mice. |
In vivo | In L6 myotubes, ZLN005 enhances glucose uptake and fatty acid oxidation by activating AMP-activated protein kinase (AMPK), and it elevates the expression of PGC-1α genes and downstream genes without significant toxicity. However, the same effects are not observed in primary rat hepatocytes, indicating cell-specific actions. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol : 2 mg/mL (7.98 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 60 mg/mL (239.67 mM) |
Keywords | inhibit | ZLN 005 | Inhibitor | PPARγ coactivator-1α | ZLN005 | PGC-1α | ZLN-005 | Autophagy |
Inhibitors Related | Stavudine | Xylitol | Myricetin | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib |
Related Compound Libraries | Glycometabolism Compound Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Autophagy Compound Library | NO PAINS Compound Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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