YB-0158 ammonium NEW
| Price | $289 | $689 | $1120 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-20 |
Product Details
| Product Name: YB-0158 ammonium | Purity: 98.74% |
| Supply Ability: 10g | Release date: 2024/11/20 |
Product Introduction
Bioactivity
| Name | YB-0158 ammonium |
| Description | YB-0158 ammonium (Wnt pathway inhibitor 2 ammonium) is a reverse-rotation peptidomimetic small molecule with translation-enhancing potential and anticancer activity. YB-0158 ammonium disrupts Sam68-Src interaction and induces apoptosis in colorectal cancer cells, which can be used to study cancer. |
| In vitro | b>METHODS: YB-0158 ammonium (0.2 μM and 0.5 μM, 48 hours) treated HT29 cells RESULTS: Lower doses of YB-0158 ammonium were sufficient to significantly reduce the proliferation of human CRC cells. When used at 0.5 μM, YB-0158 ammonium also significantly increased the apoptosis of CRC cells, as measured by the activated Caspase-3/7 detection assay. represent. [1] |
| In vivo | b>METHODS: Primary mouse recipients were treated with YB-0158 ammonium (100 mg/kg), and the presence or absence of secondary tumors was determined by live fluorescence tumor imaging. RESULTS: No significant differences in primary tumor size were observed in YB-0158 ammonium-treated mice compared to saline controls. [1] |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | YB0158ammonium |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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