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Postion:Product Catalog >UCB-5307
UCB-5307
  • UCB-5307

UCB-5307 NEW

Price $51 $122 $198
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-16

Product Details

Product Name: UCB-5307 CAS No.: 1515887-44-1
Purity: 98.02% Supply Ability: 10g
Release date: 2024/11/16

Product Introduction

Bioactivity

名稱UCB-5307
描述UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro. The KD of human TNFα is 9 nM. The TNF was directly bound by slow binding kinetics,KD= 6 nM. UCB-5307 can pass through prefabricated hTNF/hTNFR1 complexes.
體外活性UCB-5307 exhibits inhibition against wild-type TNF but does not inhibition against L57F TNF. The half-life of UCB-5307 is determined to be 3.3 hours.[1] UCB-5307 disrupts a preexisting complex between hTNF and hTNFR1, penetrating the complex and displacing one of the receptors. Prior exposure of hTNF to UCB-5307 prevents one receptor from binding.[1]
存儲(chǔ)條件Shipping with blue ice.
溶解度DMSO : 65 mg/mL (189.27 mM), Sonication is recommended.
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相關(guān)庫NF-κB 通路分子庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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