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Postion:Product Catalog >TDI-011536
TDI-011536
  • TDI-011536

TDI-011536 NEW

Price $51 $80 $172
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: TDI-011536 CAS No.: 2687970-96-1
Purity: 99.53% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTDI-011536
DescriptionTDI-011536, a potent Lats kinase inhibitor, disrupts Hippo-Yap signaling and promotes the proliferation of lesioned heart muscle cells. This compound is valuable for research in organ conservation and regeneration.
In vitroTDI-011536 (3 μM; 24 h) reduces Yap phosphorylation and (3 μM; 5 days) induces Müller glia proliferation in human retinal organoids[1].
In vivoTDI-011536 (200 mg/kg; i.p.; once) inhibits Lats and reduces pYap levels for over 4 hours in the liver, heart, and skin, while TDI-011536 (100 mg/kg; i.p.; once daily for 2 or 3 days) exhibits a proliferative effect on cardiomyocytes[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (274.41 mM)
KeywordsTDI 011536 | TDI-011536 | TDI011536
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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