Patritumab deruxtecan NEW
| Price | $797 | $2320 | $3480 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Patritumab deruxtecan | CAS No.: 2227102-46-5 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Patritumab deruxtecan |
| Description | Patritumab deruxtecan (HER3-DXd), an antibody-drug conjugate (ADC), comprises a fully human anti-HER3 IgG1 monoclonal antibody, Patritumab, linked to a topoisomerase I inhibitor payload through a tetrapeptide-based cleavable linker, demonstrating anticancer activity [1]. |
| In vitro | Patritumab deruxtecan exhibits activity against breast cancer cells expressing HER3 mutations, regardless of HER2 overexpression [1]. It binds to the surface of all HER3 mutants and HER3 WT MDA-MB-231 cells in a concentration-dependent manner (0-100 nM), but does not bind to HER3^EV cells [1]. |
| Storage | Shipping with blue ice. |
| Keywords | Patritumab deruxtecan |
| Inhibitors Related | Disitamab vedotin | Cantuzumab ravtansine | Glembatumumab vedotin | Cantuzumab mertansine | Brentuximab vedotin | Sacituzumab govitecan | Zilovertamab vedotin | N3-PEG4-C2-NHS ester | Trastuzumab deruxtecan | Tusamitamab ravtansine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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