MRK-740 NEW
Price | $105 | $172 | $372 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: MRK-740 | CAS No.: 2387510-80-5 |
Purity: 99.66% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | MRK-740 |
Description | MRK-740 is a potent and selective inhibitor of PRDM9 histone methyltransferase.MRK-740 inhibits other histone methyltransferases and inhibits PRDM9-dependent H3K4 trimethylation. |
In vitro | After 24 hours of treatment, MRK-740 (3 μM) does not affect the growth of HEK293T cells at IC90, but some toxicity is observed at 10 μM. MRK-740 serves as an equivalent inhibitor of H3K4 methylation in MCF7 cells. In cells, MRK-740 selectively and directly inhibits H3K4 methylation at endogenous PRDM9 target sites[1]. |
Storage | Shipping with blue ice. |
Solubility Information | DMSO : 30 mg/mL (64.58 mM), Sonication is recommended. |
Inhibitors Related | BIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | MAK683 | EZM 2302 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719 |
Related Compound Libraries | Bioactive Compound Library | Epigenetics Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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