740 Y-P NEW
| Price | $89 | $139 | $265 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: 740 Y-P | CAS No.: 1236188-16-1 |
| Purity: 99.87% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | 740 Y-P |
| Description | 740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K. |
| In vitro | 740 Y-P is a synthetic biotinylated peptide. 740 Y-P stimulates mitogenesis at the lowest concentration tested (1 mg/mL). The peptide stimulates mitogenesis in both the presence and absence of serum (0.5%) and in the former instance, a maximal response observed at 50 mg/mL. 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell-permeable SH2 domain-binding peptide [1]. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose-dependent and does not require insulin[2]. |
| Storage | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (15.29 mM), Sonication is recommended. H2O : 5.5 mg/mL (1.68 mM), Adjust pH with HCl and sonication is recommended. |
| Keywords | VSMC | PI3K | inhibit | alzheimer’s disease | aortic | p85 binding | SH2 | Autophagy | 740 Y P | cancer | 740 YP | peptide | 740 Y-P | Inhibitor | thoracic | Phosphoinositide 3-kinase |
| Inhibitors Related | Hydroxychloroquine | Guanidine hydrochloride |
| Related Compound Libraries | PI3K-AKT-mTOR Compound Library | Neural Regeneration Compound Library | Oxidation-Reduction Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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