ML-9 NEW
| Price | $34 | $52 | $97 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: ML-9 | CAS No.: 105637-50-1 |
| Purity: 99.6% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | ML-9 |
| 描述 | ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation. |
| 體外活性 | ML9 (50?μM; 1-4?hours) obviously enhances cleaved caspase-3 levels, reduced STIM1 protein levels by about 42%. ML9 (0-100?μM; 0-24?hours) has no reduction in cardiomyocyte viability, 50-100?μM obviously causes cell death [2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 25 mg/mL (69.2 mM) |
| 關鍵字 | viability | STIM1 | Inhibitor | ML9 | MLCK | ML-9 | caspase | Myosin | inhibit | ML 9 | cardiomyocyte |
| 相關產(chǎn)品 | Nisoldipine | Diltiazem hydrochloride | Levetiracetam | L-Ascorbic acid | Lanthanum(III) chloride heptahydrate | Artemisinin | Ethyl cinnamate | 1-Octanol | 2-Nitrobenzoic acid | 2,3-Butanediol | Methyl homoveratrate | Otilonium bromide |
| 相關庫 | 神經(jīng)再生化合物庫 | 抗胰腺癌化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 抑制劑庫 | 干細胞分化化合物庫 | NO PAINS 化合物庫 | PPI抑制劑庫 | 代謝化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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