Melanotan (MT)-II NEW
| Price | $42 | $68 | $100 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Melanotan (MT)-II | CAS No.: 121062-08-6 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Melanotan (MT)-II |
| Description | Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH). |
| In vitro | Melanotan-II (MT-II) acts as a powerful, non-selective agonist targeting melanocortin receptors (MC1, MC3, MC4, and MC5), which play crucial roles in various physiological systems including pigmentation, energy balance, sexual health, immune response, inflammation, and cardiovascular function[1]. |
| In vivo | Melanotan (MT)-II functions as a potent inducer of penile erection, demonstrating dose-dependent activity. It reduces the time until the first erectile event and enhances erectile responses following cavernous nerve stimulation. Research indicates that at a dosage of 1 mg/kg intravenously, MT-II facilitates erection by increasing the erectile response. Additionally, MT-II has been shown to possess neuroprotective qualities and promote peripheral nerve regeneration, particularly highlighted by its significant enhancement of sensory function recovery in rats after sciatic nerve damage when administered at 20 μg/kg every 48 hours subcutaneously. In cases of erectile dysfunction in men, MT-II has proven to be an effective initiator of penile erection. Beyond its effects on erectile and sensory functions, MT-II also impacts metabolic parameters, notably reducing food intake and body weight, while inducing thermogenic responses in mouse models. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mM |
| Keywords | Inhibitor | inhibit | Melanotan (MT)II | Melanotan (MT)-II | Melanotan (MT) II |
| Inhibitors Related | HS 014 acetate(207678-81-7 free base) | MCL0020 | Beta-MSH (1-22) (human) acetate | Neuropeptide EI, rat acetate | [D-Trp8]-γ-MSH acetate(321351-81-9 free base) | Undecylenoyl phenylalanine | ACTH 11-24 acetate(4237-93-8 free base) | Bremelanotide Acetate | HS024 | Nonapeptide-1 acetate salt (158563-45-2 free base) |
| Related Compound Libraries | Macrocyclic Compound Library | Cyclic Peptide Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Peptide Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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