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Postion:Product Catalog >Biochemical Engineering>Natural Products>Hypericin
Hypericin
  • Hypericin
  • Hypericin
  • Hypericin
  • Hypericin
  • Hypericin

Hypericin NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-10-14

Product Details

Product Name: Hypericin CAS No.: 548-04-9
EC-No.: 208-941-0 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/10/14

CAS:548-04-9
MF:C30H16O8
MW:504.44
EINECS:208-941-0
Product Categories:Nutraceuticals;Antitumour;Natural Plant Extract;Anthraquinones, Hydroquinones and Quinones;antibiotic;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Plant extracts;Herb extract;plant extract
Mol File:548-04-9.mol
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Hypericin Chemical Properties
Melting point 299-301°C
Boiling point 1020.3±65.0 °C(Predicted)
density 1.915±0.06 g/cm3(Predicted)
RTECS SF8472000
storage temp. -20°C
solubility 1 M NaOH: 10 mg/mL
form powder
pka6.91±0.20(Predicted)
color black
Water Solubility Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.
Sensitive Light Sensitive
Merck 14,4863
BRN 1917913
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKeyBTXNYTINYBABQR-UHFFFAOYSA-N
LogP10.827 (est)
CAS DataBase Reference548-04-9(CAS DataBase Reference)
Uses(1) Antidepressant, increase immunity.
(2) For the treatment of antidepressants, increase immunity.
DescriptionAn anthroquinone derivative that is naturally found in the flower of H. perforatum (St. John’s wort) and has antidepressant, antiviral, and anticancer activities. Hypericin inhibits neuronal uptake of serotonin, norepinephrine, dopamine, GABA and L-glutamate, contributing to its antidepressant effects. It exerts broad spectrum phototoxic affects (IC50 = 140 - 1,570 nM) through induction of apoptotic signaling and formation of reactive oxygen species (ROS) in cancer cells. Hypericin also has in vitro activity, which can be enhanced with photo-activation, against a variety of viruses including HIV, influenza virus, hepatitis C, murine cytolomegalovirus, and herpes viruses.
Chemical PropertiesPowder
UsesIt was used as reference standard in determining hypericins in St. John′s Wort using HPLC method.
DefinitionChEBI: Hypericin is a carbopolycyclic compound. It has a role as an antidepressant. It derives from a hydride of a bisanthene.
General DescriptionProduced by HWI Analytik
Exact content can be found on the certificate
Biological ActivityPhotosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC 50 = 7.5 μ M) and is preferentially cytotoxic to tumor cells upon stimulation by visible light.
Biochem/physiol ActionsPrimary TargetPKC
storage+4°C
Purification MethodsCrystallise hypericin from pyridine by addition of methanolic HCl. [Beilstein 8 IV 3761.]
References1) Kubin et al., (2005) Hypericin – the facts about a controversial agent; Current Pharm. Des., 11 233 2) Theodossiou et al., (2009) The multifaceted photocytotoxic profile of hypericin; Mol. Pharmacol., 6 1775

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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  • Since: 2017-12-08
  • Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
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