FGI-106 tetrahydrochloride NEW
| Price | $79 | $173 | $273 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: FGI-106 tetrahydrochloride | CAS No.: 1149348-10-6 |
| Purity: 98.98% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | FGI-106 tetrahydrochloride |
| 描述 | FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective concentrations (EC50s) of 100 nM, 800 nM, and 400-900 nM, respectively. Additionally, it effectively inhibits non-hemorrhagic fever viruses, notably HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively, indicating its broad-spectrum antiviral potential. |
| 體外活性 | In cell-based assays, treatment with FGI-106 inhibits viral replication by divergent virus families, including positive and negative-strand RNA viruses.Treatment with 2 μM FGI-106 mediated a 4 log reduction in infectious viral titers relative to matched controls, with an EC90 for inhibition of viral killing of host cells (Vero E6 cells) estimated to be 0.6 μM. |
| 體內(nèi)活性 | FGI-106??treatment decreases mortality from Zaire EBOV in a dose-dependent manner. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 7.5 mg/ml (12.41 mM), Sonication is recommended. |
| 關(guān)鍵字 | fever | pathogens | Ebola | Influenza Virus | inhibit | HIV-1 | replication | FGI 106 Tetrahydrochloride | HCV | hemorrhagic | Hepatitis C virus | EBOV | HIV | tetrahydrochloride | FGI106 tetrahydrochloride | FGI106 Tetrahydrochloride | Inhibitor | FGI-106 tetrahydrochloride | FGI-106 | broad-spectrum | antiviral | Human immunodeficiency virus | FGI-106 Tetrahydrochloride | lethal | FGI106 | FGI 106 tetrahydrochloride | FGI 106 |
| 相關(guān)產(chǎn)品 | Stavudine | Rifampicin | 5-Fluorouracil | Emtricitabine | Phenytoin sodium | Acetylcysteine | Kaempferol | Dextran sulfate sodium salt (MW 4500-5500) | Lamivudine | Curcumin | Decanedioic acid | Crystal Violet |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 抗病毒庫 | 抑制劑庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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