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Postion:Product Catalog >ErSO
ErSO
  • ErSO

ErSO NEW

Price $68 $173 $277
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: ErSO CAS No.: 2407860-35-7
Purity: 98.11% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameErSO
DescriptionErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.
In vitroIn MCF-7 cells, ErSO (1-1000 nM) inhibits cell viability with an IC50 of 20.3 nM. ErSO (1 μM) rapidly kills ERα-positive breast cancer cells in TYS and TDG cells and induces rapid killing of ERα-positive MCF-7 human breast cancer cells[1].
In vivoErSO (10 and 40 mg/kg; p.o.) induces >100000-fold regression (to undetectable amounts) within 14 days and >10000-fold regression of TYS-luciferase-expressing breast tumors in all five mice. In Nu/J mice, ErSO (10 or 40 mg/kg; p.o.) eliminates tumors with >90% reduction in all cases[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (220.6 mM), Sonication is recommended.
KeywordsErSO
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
2024-10-22
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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