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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Eplerenone
Eplerenone
  • Eplerenone
  • Eplerenone
  • Eplerenone
  • Eplerenone
  • Eplerenone

Eplerenone NEW

Price $301 $270 $250
Package 10g 100g 1000g
Min. Order: 1g
Supply Ability: 8000g
Update Time: 2024-12-12

Product Details

Product Name: Eplerenone CAS No.: 107724-20-9
EC-No.: 600-850-8 Min. Order: 1g
Purity: 99% Supply Ability: 8000g
Release date: 2024/12/12

Eplenone selectively acts on aldosterone receptors and is highly selective to salocorticoid receptors, but has less effect on androgen and progesterone receptors. Its affinity for salocorticoid is 15 to 20 times that of spironolactone, and its affinity for androgen and progesterone receptors is 500 times smaller than spironolactone, so there are fewer sex hormone-related adverse reactions. Eplenone can reduce hypertension. Since aldosterone may play an important role in the pathophysiological process of obesity-induced hypertension, Eplenone also has a good antihypertensive effect on diet-induced obesity-related hypertension. In addition, eplenone significantly reduces the ultrafiltration effect of the glomerulus and therefore reduces proteinuria in patients with high Chemicalbook blood pressure, and this renal protective effect is more pronounced in patients with hypertension combined with diabetes. Eplenone is not an inhibitor of CYP1A2, CYP3A4, CYP2C19, CYP2C9, or CYP2D6. It does not inhibit the metabolism of dichlorophenolic acid, methylphenidate, losartan, amiodarone, dexamethasone, phenytoin sodium, phenacetin, dextromethorphan, metoprolol, metobutamide, amlodipine, astimazole, Ciszapide, Diazepam, 17-acetylidiol estradiol, fluoxetine, lovastatin, methylprednisolone, midazolam, Nifedipine, glibenuride and warfarin.

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Company Profile Introduction

-.Hebei Dangtong Biological Technology Co.,LTD founded in April 2004,has more than 960employees. Headquartered in Luquan District, Shijiazhuang city,Hebei Province, weare a professional manufacturer of alkaline dyes, chemical raw materials, foodadditives and pharmaceutical intermediates. The company has 3 production bases. Respectively in Hebei, Inner Mongolia, Yunnan three factory bases. It has two research centers and three laboratories specializing in the development of new products and the optimization of existing products. Committed to providing higher quality products and services to meet customer personalized needs. In terms of production, the company insists on integrated production, supplying main raw materials by itself, and laying out lean factories to ensure sustainable and stable supply.

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  • Since: 2021-05-08
  • Address: Room 10-0-1001, Chunbei District, Shunde North Road, Xiangdu District, Xingtai city, Hebei Province
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