Product Details
Product Name:
Dorzagliatin |
CAS No.:
1191995-00-2 |
Purity:
98.67% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Dorzagliatin |
Description | Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes. |
In vivo | In diabetic rats, Dorzagliatin (low-dose 10?mg/kg, and high-dose 30?mg/kg; administered intragastrically; daily 8:00 AM for one month) shows a glucose-lowering effect on the glucose levels[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 125 mg/mL (270.02 mM), Sonication is recommended.
|
Keywords | diabetes | inhibit | β-cell | Hexokinase IV | Inhibitor | glycaemic | type 2 | Hexokinase D | Glucokinase | pancreatic | HMS-5552 | Dorzagliatin | HMS 5552 |
Inhibitors Related | ARRY-403 | Globalagliatin | ML251 | PFK-015 | 3PO | PFKFB3-IN-2 | Oxfendazole | AZ PFKFB3 26 | AMG-1694 | PFK-158 | (1S,2R)-Globalagliatin | PF-04937319 |
Related Compound Libraries | Bioactive Compound Library | Anti-Diabetic Compound Library | Kinase Inhibitor Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Preclinical Compound Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$7.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-01-13 |