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Postion:Product Catalog >Analytical Chemistry>Analysis reagents>General Analytical Reagents>Calcimycin
Calcimycin
  • Calcimycin

Calcimycin NEW

Price $62
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: Calcimycin CAS No.: 52665-69-7
Purity: 98% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱Calcimycin
描述Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes, uncouples oxidative phosphorylation, and inhibits ATPase of rat liver mitochondria. The substance is primarily used as a biochemical tool to study the role of divalent cations in various biological systems.
體外活性Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner [4].
體內(nèi)活性Calcimycin (2.5 or 7.5 nM; intrapleurally) induces protein leakage [5].
存儲(chǔ)條件store at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 47 mg/mL (89.76 mM), Sonication is recommended.
關(guān)鍵字phosphorylation | Inhibitor | Antibiotic A23187 | bacteria | A 23187 | Bacterial | mycobacterial | Autophagy | Apoptosis | divalent | Antibiotic A 23187 | inhibit | Antibiotic | Calcimycin | A23187 | cation | ionophore | Gram-positive | Fungal
相關(guān)產(chǎn)品Neomycin sulfate | Dimethyl sulfoxide
相關(guān)庫細(xì)胞凋亡化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$62.00/1mg
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TargetMol Chemicals Inc.
2024-11-15
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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