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Postion:Product Catalog >BT-13
BT-13
  • BT-13

BT-13 NEW

Price $36 $52 $88
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: BT-13 CAS No.: 924537-98-4
Purity: 99.23% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBT-13
DescriptionBT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro.
In vitroBT-13 stimulates phosphorylation of RET and RET-dependent intracellular signaling, but does not activate the BDNF receptor TrkB, the NGF receptor TrkA, or associated intracellular signaling in the absence of RET.
In vivoIn rats with surgery-induced neuropathy, BT-13 (20 and 25mg/kg in rats induced by ligation of left L5 and L6 spinal nerves) has a slight antinociceptive/antihyperalgesic effect and protected DRG neurons.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 25 mg/mL (48.31 mM), Sonication is recommended.
KeywordsRET | BT-13 | BT 13 | Inhibitor | inhibit | BT13
Inhibitors RelatedCabozantinib | Fedratinib | Regorafenib monohydrate | Regorafenib Hydrochloride | SGI-7079 | Regorafenib | AST 487 | Amuvatinib | ON123300 | Lenvatinib mesylate | Lenvatinib | Selpercatinib
Related Compound LibrariesApoptosis Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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