BT-13 NEW
Price | $36 | $52 | $88 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: BT-13 | CAS No.: 924537-98-4 |
Purity: 99.23% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | BT-13 |
Description | BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro. |
In vitro | BT-13 stimulates phosphorylation of RET and RET-dependent intracellular signaling, but does not activate the BDNF receptor TrkB, the NGF receptor TrkA, or associated intracellular signaling in the absence of RET. |
In vivo | In rats with surgery-induced neuropathy, BT-13 (20 and 25mg/kg in rats induced by ligation of left L5 and L6 spinal nerves) has a slight antinociceptive/antihyperalgesic effect and protected DRG neurons. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 25 mg/mL (48.31 mM), Sonication is recommended. |
Keywords | RET | BT-13 | BT 13 | Inhibitor | inhibit | BT13 |
Inhibitors Related | Cabozantinib | Fedratinib | Regorafenib monohydrate | Regorafenib Hydrochloride | SGI-7079 | Regorafenib | AST 487 | Amuvatinib | ON123300 | Lenvatinib mesylate | Lenvatinib | Selpercatinib |
Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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