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Postion:Product Catalog >BAY-678
BAY-678
  • BAY-678

BAY-678 NEW

Price $55 $97 $213
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: BAY-678 CAS No.: 675103-36-3
Purity: 98.25% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBAY-678
DescriptionBAY-678 is a human neutrophil elastase (HNE; IC50: 20 nM) inhibitor with oral bioactivity, potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC).
In vitroBAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium.[2] The Ki value of BAY-678 for MNE is 700 nM. BAY-678 is the 4th generation inhibitor of HNE.[1]
In vivoBAY-678 reveals significant efficacy in preclinical models of ALI and lung emphysema. Additionally, BAY-678 has shown significant beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice.[2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (224.8 mM)
Ethanol : 4.3 mg/mL (10.7 mM)
KeywordsBAY 678 | BAY-678 | BAY678
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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