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Postion:Product Catalog >Anticancer agent 73
Anticancer agent 73
  • Anticancer agent 73

Anticancer agent 73 NEW

Price $47 $80 $163
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-16

Product Details

Product Name: Anticancer agent 73 CAS No.: 124811-87-6
Purity: 99.19% Supply Ability: 10g
Release date: 2024/11/16

Product Introduction

Bioactivity

名稱Anticancer agent 73
描述Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
體外活性Anticancer agent 73 (compound CIB-3b) (10 μM; 6 h) elevates E-cadherin expression and reduces fibronectin, N-cadherin, and vimentin protein levels in SK-HEP-1 cells. It also inhibits the proliferation and migration of SK-HEP-1, HCCLM3, and MHCC97L cells by impeding miRNA biogenesis.[1]
體內(nèi)活性Anticancer agent 73 (compound CIB-3b) (10, 25, and 50 mg/kg; i.v.; every 2 days for 4 weeks; SCID mice) diminishes the proliferation and migration of both SK-HEP-1 cells and SK-HEP-1 cells implanted in SCID mice.[1]
存儲條件Shipping with blue ice.
溶解度DMSO : 90.0 mg/mL (344.5 mM), Sonication is recommended.
相關(guān)產(chǎn)品Rifampicin | 5-Fluorouracil | Ribavirin | Guanidine hydrochloride | 2,4-D | Resveratrol | Acyclovir | Thymidine | Temozolomide | Folic acid
相關(guān)庫經(jīng)典已知活性庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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