Anticancer agent 43 NEW
| Price | $84 | $139 | $233 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-12 |
Product Details
| Product Name: Anticancer agent 43 | CAS No.: 2470015-35-9 |
| Purity: 98.88% | Supply Ability: 10g |
| Release date: 2024/11/12 |
Product Introduction
Bioactivity
| 名稱 | Anticancer agent 43 |
| 描述 | Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in rats. |
| 體外活性 | Anticancer agent 43 (compound 3a) selectively targets human tumor cells, exhibiting an SI50 of 28.94[1]. In HepG2 cells treated with 45 μM for 24 hours, it induces apoptosis via caspase 3, PARP1, and Bax-dependent pathways without affecting the G1/S phase transition[1]. It also causes DNA damage in HCT116, MCF-7, HepG2, and Balb/c 3T3 cells at concentrations of 0.7, 45, and 55 μM, as evidenced by tail DNA and Olive Tail Moment (OTM) measurements[1]. |
| 存儲條件 | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/mL (297.30 mM), Sonication is recommended. |
| 相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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