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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Clonidine hydrochloride
Clonidine hydrochloride
  • Clonidine hydrochloride

Clonidine hydrochloride

Price $1
Package 1kg
Min. Order: 1g
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Clonidine hydrochloride CAS No.: 4205-91-8
Min. Order: 1g Purity: 99%
Supply Ability: 100KG Release date: 2019/07/06
Product:: AD68
Clonidine hydrochloride Basic information
Product Name: Clonidine hydrochloride
Synonyms: TIMTEC-BB SBB003065;CLONIDINE HCL;CLONIDINE HYDROCHLORIDE;DIXARIT;2-[2,6-DICHLOROANILINE]-2-IMIDAZOLINE HYDROCHLORIDE;2-(2,6-DICHLOROANILINO)-2-IMIDAZOLINE, HCL;2-(2,6-DICHLOROANILINO)-2-IMIDAZOLINE HYDROCHLORIDE;2-(2,6-DICHLOROPHENYLAMINO)-2-IMIDAZOLINE HYDROCHLORIDE
CAS: 4205-91-8
MF: C9H10Cl3N3
MW: 266.55
EINECS: 224-121-5
Product Categories: Adrenoceptor;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;CATAPRES;Other APIs
Mol File: 4205-91-8.mol
Article illustration
 
Clonidine hydrochloride Chemical Properties
Melting point  312 °C
storage temp.  2-8°C
solubility  H2O: 50 mg/mL, clear, colorless
color  white
Water Solubility  Soluble in water (50 mg/ml), DMSO (75 mM), methanol, chloroform (slightly), and dehydrated alcohol.
Merck  14,2390
InChIKey GLEWMLFXCSBZLK-UHFFFAOYSA-N
CAS DataBase Reference 4205-91-8(CAS DataBase Reference)
 
Safety Information
Hazard Codes  T+
Risk Statements  25-26
Safety Statements  22-26-28-36/37/39-45
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  NJ2490000
10
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice, rats (mg/kg): 328, 270 orally; 18, 29 i.v. (Walland)
MSDS Information
Provider Language
SigmaAldrich English
 
Clonidine hydrochloride Usage And Synthesis
Chemical Properties White Solid
Uses Labelled Clonidine. α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.
Uses `a2-adrenoceptor agonist, imidazoline receptor ligand, anti-hypertensive
Uses In shaving soaps.
Brand name Catapres (Boehrin- ger Ingelheim); Duraclon (Xanodyne).
Biological Activity Prototypical I 1 imidazoline receptor ligand. α 2 -adrenergic receptor agonist. Antihypertensive.
Purification Methods This antihypertensive is recrystallised from EtOH/Et2O and dried in a vacuum (solubility in H2O is 5%). The free base has m 124-125o and is recrystallised from hexane. [Jen et al. J Med Chem 18 90 1975, NMR: Jackman & Jen J Am Chem Soc 97 2811 1975.]

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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