5-Bromovaleryl Chloride (CAS: 4509-90-4)

Physical and Chemical Properties

Chemical Information

• IUPAC Name: 5-Bromopentanoyl chloride

• Synonyms: 5-Bromo-pentanoyl chloride, Valeryl chloride, 5-bromo-

• Molecular Formula: C5H8BrClO

• Molecular Weight: 199.47 g/mol

Structure and Properties

• Chemical Structure: The compound consists of a pentanoyl chloride moiety with a bromine atom attached to the fifth carbon atom.

• Appearance: Typically a colorless to pale yellow liquid.

• Boiling Point: Approximately 208-210°C

• Density: Approximately 1.516 g/mL at 25°C

• Refractive Index: n20/D 1.502 (literature value)

Applications and Uses

• Chemical Synthesis: Used as an intermediate in organic synthesis, especially for the introduction of the 5-bromopentanoyl group into molecules.

• Pharmaceuticals: Potential applications in the synthesis of pharmaceutical compounds where such a moiety is required.

• Research: Employed in research to study the properties and reactions of brominated acyl chlorides and related compounds.

Safety and Handling

• Personal Protective Equipment (PPE): Use appropriate gloves, protective eyewear, and lab coats to prevent contact with skin and eyes. Work in a fume hood to avoid inhalation.

• Storage: Store in a cool, dry place, tightly closed, and away from incompatible substances such as strong bases and oxidizing agents.

• Hazards:

• Corrosive: Can cause severe skin burns and eye damage.

• Inhalation: Harmful if inhaled, causing respiratory tract irritation.

• Handling: Handle with care, avoiding any form of contact and inhalation.

• First Aid Measures:

• Inhalation: Move to fresh air. If breathing is difficult, give oxygen and seek medical attention.

• Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. Remove contaminated clothing and seek medical attention.

• Eye Contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

• Ingestion: Do not induce vomiting. Rinse mouth with water and seek medical attention immediately.

References and Resources

5-Bromovaleryl chloride is valuable in various industrial and research applications due to its unique chemical structure and reactivity. For precise safety guidelines and detailed information, always refer to the specific Material Safety Data Sheet (MSDS) provided by the manufacturer or supplier.