Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate (CAS: 143878-29-9)

Physical and Chemical Properties

Chemical Information

• IUPAC Name: Methyl 4-acetamido-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate

• Synonyms: Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

• Molecular Formula: C12H12ClNO4

• Molecular Weight: 269.68 g/mol

Structure and Properties

• Chemical Structure: The compound consists of a benzofuran core with an acetamido group at the 4-position, a chlorine atom at the 5-position, and a carboxylate ester group at the 7-position.

• Appearance: Typically a white to off-white crystalline powder or solid.

• Melting Point: Specific data may vary but generally within a common range for similar compounds.

Applications and Uses

• Pharmaceuticals: Used as an intermediate in the synthesis of various pharmaceutical compounds, particularly those involving benzofuran moieties.

• Chemical Research: Utilized in research to study the properties and reactions of substituted benzofurans, which have potential applications in medicinal chemistry.

• Organic Synthesis: Employed as a building block in the synthesis of more complex organic molecules.

Safety and Handling

• Personal Protective Equipment (PPE): Use appropriate gloves, protective eyewear, and lab coats to prevent contact with skin and eyes.

• Storage: Store in a cool, dry place, away from incompatible substances such as strong oxidizing agents.

• Hazards: Can cause skin and eye irritation. Inhalation of dust may cause respiratory tract irritation.

• First Aid Measures:

• Inhalation: Move to fresh air. If not breathing, give artificial respiration and seek medical attention.

• Skin Contact: Wash off with soap and plenty of water. Remove contaminated clothing and shoes.

• Eye Contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

• Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical attention.

References and Resources

Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is valuable in various industrial and research applications due to its unique chemical structure and reactivity. For precise safety guidelines and detailed information, always refer to the specific Material Safety Data Sheet (MSDS) provided by the manufacturer or supplier.