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Postion:Product Catalog >API>Antibiotics>Tetracycline drugs>Tetracycline
Tetracycline
  • Tetracycline
  • Tetracycline

Tetracycline

Price $1
Package 1KG
Min. Order: 1G
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Tetracycline CAS No.: 60-54-8
Min. Order: 1G Purity: 98%
Supply Ability: 100KG Release date: 2019/07/06

AD68

Tetracycline Basic information
Product Name: Tetracycline
Synonyms: 12,12a-pentahydroxy-6-methyl-1,11-dioxo-1;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide;4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-4-(dimethylamino)-4;6-methyl-1,11-dioxy-2-naphthacenecarboxamide;abramycin;abricycline;achromycin(naphthacenederivative);achromycin(naphthracenederivatives)
CAS: 60-54-8
MF: C22H24N2O8
MW: 444.44
EINECS: 200-481-9
Product Categories: Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics T-ZAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Tetracyclines;Peptide Synthesis/Antibiotics;Inhibitors
Mol File: 60-54-8.mol
Article illustration
 
Tetracycline Chemical Properties
Melting point  175-177 °C(lit.)
alpha  D25 -257.9° (0.1N HCl); D25 -239° (methanol)
Boiling point  554.44°C (rough estimate)
density  1.3809 (rough estimate)
refractive index  1.6500 (estimate)
storage temp.  2-8°C
solubility  95% ethanol: soluble12.5mg/mL
pka pKa (50% aq DMF): 8.3, 10.2(at 25℃)
color  yellow to yellow orange
Water Solubility  Limited solubility in water. Soluble in 1M HCl with heating.
Merck  13,9271
CAS DataBase Reference 60-54-8(CAS DataBase Reference)
NIST Chemistry Reference Tetracycline(60-54-8)
EPA Substance Registry System 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,6, 10,12,12a-pentahydroxy-6- methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-(60-54-8)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-36-26
WGK Germany  3
RTECS  QI8750000
3-8-10
HS Code  29413000
Hazardous Substances Data 60-54-8(Hazardous Substances Data)
Toxicity LD50 in rats, mice (mg/kg): 807, 808 orally (Goldenthal)
Tetracycline Usage And Synthesis
Chemical Properties Crystalline Solid
Uses antibactierial
Uses antibacterial, antiamebic, antirickettsial
Uses Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products.
Uses Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.
Uses Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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