- Climbazole
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- $999.00/ kg
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2024-12-22
- CAS:38083-17-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- Climbazole
-
- $6.00 / 1kg
-
2024-12-20
- CAS:38083-17-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000KG/Month
- Climbazole
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- $0.00 / 25KG
-
2024-12-20
- CAS:38083-17-9
- Min. Order: 1KG
- Purity: ≥99.5%
- Supply Ability: 200mt/year
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| | Climbazole Chemical Properties |
| Melting point | 96-100°C | | Boiling point | 447.5±40.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | vapor pressure | 0.001Pa at 25℃ | | refractive index | 1.54 | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Insoluble in water | | form | Solid | | pka | 5.66±0.22(Predicted) | | color | White to Almost white | | Water Solubility | 58mg/L at 25℃ | | BRN | 618020 | | InChIKey | OWEGWHBOCFMBLP-UHFFFAOYSA-N | | LogP | 3.83 at 25℃ | | CAS DataBase Reference | 38083-17-9(CAS DataBase Reference) |
| Hazard Codes | Xn,N | | Risk Statements | 22-50/53 | | Safety Statements | 60-61 | | RIDADR | UN 3077 | | WGK Germany | 3 | | RTECS | EL7085000 | | HS Code | 29332900 |
| | Climbazole Usage And Synthesis |
| Risks to the environment | Climbazole (CBZ) is an emerging recalcitrant contaminant in wastewater, which has severe toxic effects on aquatic organisms. | | Description | (±)-Climbazole is an imidazole antifungal agent. It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = <0.06-1 μg/ml) and M. furfur (MICs = <0.06-0.5 μg/ml) in vitro. It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo. (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver. Formulations containing climbazole have been used in the treatment of dandruff. | | Chemical Properties | White Solid | | Uses | Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix.
s assay and did not induce micronuclei in human lymphocytes. | | Definition | ChEBI: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one is a ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3. It is a member of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone and a hemiaminal ether. | | Hazard | Moderately toxic by ingestion. Low toxicity by skin contact. | | Flammability and Explosibility | Non flammable | | Side effects | May cause localized irritation of the skin with symptoms including redness, rashes and itching. |
| | Climbazole Preparation Products And Raw materials |
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