8-PRENYLGENISTEIN manufacturers
- Lupiwighteone
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- $159.00 / 1mg
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2024-11-19
- CAS:104691-86-3
- Min. Order:
- Purity: 99.20%
- Supply Ability: 10g
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| | 8-PRENYLGENISTEIN Basic information |
| Product Name: | 8-PRENYLGENISTEIN | | Synonyms: | 8-PRENYLGENISTEIN;5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;3-(4-Hydroxyphenyl)-5,7-dihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;4',5,7-Trihydroxy-8-isopentenylisoflavone;4',5,7-Trihydroxy-8-prenylisoflavone;8-Isopentenylgenistein;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-;Luncheonette | | CAS: | 104691-86-3 | | MF: | C20H18O5 | | MW: | 338.35 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | Mol File |  |
| | 8-PRENYLGENISTEIN Chemical Properties |
| Melting point | 133-135℃ | | Boiling point | 583.5±50.0 °C(Predicted) | | density | 1.351±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 100 mg/mL (295.55 mM; Need ultrasonic) | | form | Powder | | pka | 6.62±0.20(Predicted) | | color | Off-white to light yellow |
| | 8-PRENYLGENISTEIN Usage And Synthesis |
| Uses | Lupiwighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol. | | Definition | ChEBI: Lupiwighteone is a member of isoflavones. | | target | PARP | Bcl-2/Bax | Caspase | Akt | CDK | ROS | P450 (e.g. CYP17) |
| | 8-PRENYLGENISTEIN Preparation Products And Raw materials |
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