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| | (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Basic information |
| Product Name: | (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline | | Synonyms: | (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline;(R)-1-(3,4-dimethoxybenzyl)-;cis-Atracurium EP Impurity C;Cisatracurium Besilate EP Impurity C;AtracuriuM Besylate iMpurity C;Cisatracurium Besilate EP Impurity C (R-Laudanosine);Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R)-;(R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium | | CAS: | 85-63-2 | | MF: | C21H27NO4 | | MW: | 357.44 | | EINECS: | | | Product Categories: | | | Mol File: | 85-63-2.mol |  |
| | (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties |
| solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated), Ethanol (Slightly), Methanol | | form | Solid | | color | White to Off-White |
| | (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Usage And Synthesis |
| Uses | (R)-Laudanosine is an isomer of (S)-Laudanosine (L178525), a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity. | | Definition | ChEBI: (R)-laudanosine is a benzylisoquinoline alkaloid that is (R)-tetrahydropapaverine in which the amino hydrogen has been replaced by a methyl group It is a polyether, a benzylisoquinoline alkaloid, a benzyltetrahydroisoquinoline, an aromatic ether and a tertiary amino compound. It is functionally related to a (R)-tetrahydropapaverine. It is a conjugate base of a (R)-laudanosine(1+). |
| | (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline Preparation Products And Raw materials |
| Raw materials | (R)-(+)-Tetrahydropapaverine-->Acetamide, N-(2-(3,4-dimethoxyphenyl)ethyl)-2,2,2-trifluoro--->3',4'-DIMETHOXYPHENYL ACETYLENE-->3,4-DIMETHOXYIODOBENZENE-->Dimethyl dicarbonate-->1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline-->Formaldehyde-->3,4-Dimethoxyphenethylamine-->1,2-Dimethoxybenzene | | Preparation Products | laudanosine |
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