D-谷氨酸
| 中文名稱 | D-谷氨酸 |
|---|---|
| 中文同義詞 | D-谷氨酸(試劑);D-麩胺酸;D-2-氨基戊二酸;D-麩氨酸;D-麩質(zhì)酸;D-Α-氨基戊二酸,D-Α-AMINOPENTANEDIOIC ACID;D-谷氨酸, 99+%;D-谷氨酸/Α-氨基戊二酸 |
| 英文名稱 | D(-)-Glutamic acid |
| 英文同義詞 | (2R)-2-Aminoglutaric acid;D-α-AMinoglutaric acid;D-1-AMinopropane-1,3-dicarboxylic acid;D(-)-GlutaMic acid, 99+% 25GR;D(-)-GlutaMic acid, 99+% 5GR;(2R)-GlutaMic Acid;NSC 77686;D-Glutaminic acid |
| CAS號 | 6893-26-1 |
| 分子式 | C5H9NO4 |
| 分子量 | 147.13 |
| EINECS號 | 230-000-8 |
| 相關(guān)類別 | 中間體;醫(yī)藥原料;天然氨基酸極其衍生物;氨基酸衍生物;氨基酸及其衍生物;生化試劑;生物化學(xué)品;氨基酸;化學(xué)生物學(xué);植物提取物;氨基酸類;其他生化試劑;醫(yī)藥中間體;保護(hù)氨基酸;非天然氨基酸;Amino ACIDS SERIES;Glutamate receptor;amino acid;中藥對照品;生化試劑-氨基酸類;化學(xué)試劑;有機(jī)原料;醫(yī)用原料;原料;生化研究試劑;生化試劑-氨基酸;標(biāo)準(zhǔn)品;有機(jī)合成原料;D-氨基酸;有機(jī)中間體;有機(jī)化工原料;化工原料;原料藥;通用生化試劑-氨基酸;對照品;Glutamic acid [Glu, E];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Nutritional Supplements;Amino Acids |
| Mol文件 | 6893-26-1.mol |
| 結(jié)構(gòu)式 |  |
D-谷氨酸 性質(zhì)
| 熔點(diǎn) | 200-202 °C (subl.)(lit.) |
|---|---|
| 比旋光度 | -31.3 º (c=10, 2 N HCl) |
| 沸點(diǎn) | 267.21°C (rough estimate) |
| 密度 | 1.5380 |
| 折射率 | 1.4210 (estimate) |
| 儲存條件 | Keep in dark place,Sealed in dry,Room Temperature |
| 溶解度 | 可微溶于水 |
| 形態(tài) | 粉末 |
| 酸度系數(shù)(pKa) | pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C) |
| 顏色 | 白色至類白色 |
| 水溶解性 | 7 g/L (20 ºC) |
| Merck | 14,4469 |
| BRN | 1723800 |
| InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
| LogP | -0.969 (est) |
| CAS 數(shù)據(jù)庫 | 6893-26-1(CAS DataBase Reference) |
| NIST化學(xué)物質(zhì)信息 | D-Glutamic acid(6893-26-1) |
| EPA化學(xué)物質(zhì)信息 | D-Glutamic acid (6893-26-1) |
|
Human Endogenous Metabolite
|
Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
安全信息
| 危險品標(biāo)志 | Xi |
|---|---|
| 危險類別碼 | 36/37/38 |
| 安全說明 | 24/25-36-26 |
| WGK Germany | 3 |
| F | 10 |
| TSCA | Yes |
| 海關(guān)編碼 | 29224200 |
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